Hochschule Reutlingen

Deep Multimodality Image-Guided System for Assisting Neurosurgery (DeepIGN)

DeepIGN is a comprehensive AI-supported image-guided neurosurgery (IGN) system that integrates pre-operative MRI data, real-time intra-operative ultrasound (iUS), and positional instrument tracking to assist neurosurgeons. The project focuses on challenging aspects of medical image processing, including brain tumor segmentation, multimodal registration of images, and the explainability of Artificial Intelligence (AI) and deep learning models. It features an open-source deep learning framework (DeepSeg) that automatically and accurately delineates brain tumors (gliomas). To compensate for tissue deformation during surgery, it uses a fast, automated approach (iRegNet) for registering pre-operative MRI to intra-operative ultrasound volumes. Furthermore, it integrates an Explainable AI framework (NeuroXAI) that provides understandable visual explanations for the AI models' predictions, significantly increasing medical experts' trust.

Laufzeit

April 2019 – March 2023

Fördergeber

German Academic Exchange Service (DAAD)

Projektkoordinator

Hochschule Reutlingen (PI: Ramy Zeineldin)

Projektpartner

Karlsruhe Institute of Technology (KIT), Klinik für Neurochirurgie BKH Günzburg, Ulm University Hospital

Auszeichnungen & Links

  • The dissertation behind this project won the best Informatik Dissertation by KIT (by der Erika und Dr. Wolfgang Eichelberger Stiftung) and was defended with summa cum laude in February 2023.
  • The work "Towards Automated Correction of Brain Shift Using Deep Deformable MRI-IUS Registration" won the first prize at the 19th Annual Conference of the German Society for Computer- and Robot-Assisted Surgery e.V..
  • The project's segmentation methods became the winner of the international MICCAI BraTS challenge in 2022, outperforming more than 1000 international teams.

Ihr Ansprechpartner

Informatik, insbesondere Medizinische Informatik